The method in brief

What it isA concentrate of platelets and fibrin from your own blood
Difference from PRPDifferent centrifugation, no anticoagulant; a fibrin clot forms
Where usedDentistry and maxillofacial surgery; in orthopaedics, some clinics
What is known in orthopaedicsAlmost no randomised trials; no proven advantage over PRP
ProcedureBlood draw, centrifugation, injection; 30–60 minutes, outpatient

CGF or PRP

  • If a clinic offers CGF, ask which studies it relies on for your diagnosis.
  • For knee osteoarthritis PRP is better studied; CGF can be seen as a variant of it.
  • CGF often costs more, and the added benefit is not confirmed.
  • Contraindications are the same as for PRP: blood disorders, anticoagulants, infection, cancer.

More on the technology on the CGF page. We request offers from several clinics and help you compare.

Scientific evidence

Evidence on platelet concentrates this page is based on:

  1. Belk JW et al. Platelet-rich plasma versus hyaluronic acid for knee osteoarthritis: a systematic review and meta-analysis of randomized controlled trials. Am J Sports Med, 2021.
  2. Bannuru RR et al. OARSI guidelines for the non-surgical management of knee, hip, and polyarticular osteoarthritis. Osteoarthritis Cartilage, 2019.

Frequently asked questions about CGF

Is CGF stronger than PRP?
This claim is not supported by orthopaedic studies.
How many sessions are needed?
Usually 1–3, as with PRP; the clinic doctor sets the exact plan.
Are there risks?
As with PRP: pain and swelling after the injection, rarely infection.
How can RegenPAS help?
RegenPAS is a patient service centre in Munich, not a clinic. We review your images and symptoms and send a request to several partner clinics at once. Clinics that can accept you send their own conditions and price; prices differ between clinics, and you choose the option that suits you. The coordinator replies within 24 hours, and a clinic physician’s preliminary opinion follows in 1–3 business days. We then arrange the appointment, visa invitation, interpreter, transfers and accommodation. Treatment decisions are made by the clinic physician. Contact a coordinator.

Related conditions and treatments

CGF technologyPRP therapyPRP, CGF, BMAC and SVFPRP or hyaluronic acidEvidenceAll treatments

Have you been offered CGF? Send your images and the offer — we will compare with other clinics

Send your MRI or ultrasound and describe where and when it hurts. The coordinator replies within 24 hours; a clinic physician gives an opinion in 1–3 business days.

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