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The method in brief
| What it is | Fragmented fat tissue of your own; without enzymatic processing it counts as medical practice in the EU |
| How it is done | Liposuction under local anaesthesia, fat processing, joint injection; 1–2 hours, outpatient |
| Who it is offered to | Moderate knee or hip osteoarthritis when exercise and simple injections have not helped |
| What studies show | Less pain in some patients; in a 2025 meta-analysis MFAT was no better than PRP and BMAC |
| Recovery | Bruising and soreness at the harvest site for 1–2 weeks |
Risks and limitations
- Bruising, swelling, soreness at the liposuction site; rarely infection.
- It does not grow cartilage and does not replace joint replacement in severe osteoarthritis.
- More expensive than PRP; usually self-paid.
- Figures such as “15–20 million stem cells” say nothing about the treatment result.
More on the technology on the MFAT (Lipogems) page. We request offers from several clinics and help you compare.
Scientific evidence
Reviews and meta-analyses this page is based on:
- Hohmann E et al. Microfragmented adipose tissue has no advantage over platelet-rich plasma and bone marrow aspirate injections for symptomatic knee osteoarthritis. Am J Sports Med, 2025.
- Ye X et al. Microfragmented adipose tissue versus platelet-rich plasma in the treatment of knee osteoarthritis: a systematic review. Acta Orthop Belg, 2024.
- Pas HI et al. Stem cell injections in knee osteoarthritis: a systematic review of the literature. Br J Sports Med, 2017.
Frequently asked questions about MFAT
Is MFAT stem cell therapy?
Fat tissue contains progenitor cells, but MFAT is tissue, not isolated or laboratory-expanded cells.
Is MFAT better than PRP?
Available comparative studies say no. PRP is cheaper and better studied.
How long does the effect last?
It varies; some patients have less pain for months, others see no effect.
How can RegenPAS help?
RegenPAS is a patient service centre in Munich, not a clinic. We review your images and symptoms and send a request to several partner clinics at once. Clinics that can accept you send their own conditions and price; prices differ between clinics, and you choose the option that suits you. The coordinator replies within 24 hours, and a clinic physician’s preliminary opinion follows in 1–3 business days. We then arrange the appointment, visa invitation, interpreter, transfers and accommodation. Treatment decisions are made by the clinic physician. Contact a coordinator.
Have you been offered MFAT? Send your images — we will get opinions from several clinics
Send your MRI or ultrasound and describe where and when it hurts. The coordinator replies within 24 hours; a clinic physician gives an opinion in 1–3 business days.
Send images